Research
Blueberries and Aging 1
Written by Administrator    Monday, 10 November 2008 08:14    PDF Print E-mail
Monday, 10 November 2008 08:14
Studies of older laboratory animals consuming blueberry supplemented diets have shown measureable improvements in memory, coordination and balance. Research at the USDA Human Nutrition Research Center has also shown neuron regeneration in older animals.

Joseph JA, Denisova NA, Arendash G, Gordon M, Diamond D, Shukitt-Hale B, Morgan D.
Blueberry supplementation enhances signaling and prevents behavioral deficits in an Alzheimer disease model. Nutritional Neuroscience, 2003, 6:153-162.

 Based on data from this study the research states, "...it may be possible to overcome genetic predispositions to Alzheimer disease through diet." The researchers fed blueberry supplemented diets to transgenic mice that develop cognitive loss and deposits in the brain similar to that seen in Alzheimer disease. Those fed blueberry supplemented diets (2% supplementation of the control diet, from 4 to 12 months of age) showed less impairment of cognitive function than those fed the control diet.

--US HIGHBUSH BLUEBERRY COUNCIL
 
Omega-3 fatty acids improve glucose tolerance and components of the metabolic syndrome in Alaskan Eskimos: the Alaska Siberia project.
Written by Administrator    Monday, 10 November 2008 08:51    PDF Print E-mail
Monday, 10 November 2008 08:51
Ebbesson SO, Risica PM, Ebbesson LO, Kennish JM, Tejero ME.
Department of Neurological Surgery, University of Virginia, Charlottesville 22908-0212
PubMed Reference
High consumption of omega-3 FAs positively affects components of the MS, insulin sensitivity and glucose tolerance. This finding suggests that high consumption of C20-C22 omega-3 FAs protects against the development of the MS and glucose intolerance.
Last Updated ( Monday, 10 November 2008 09:46 )
 
Blueberries and Aging 2
Written by Administrator    Monday, 10 November 2008 12:08    PDF Print E-mail
Monday, 10 November 2008 12:08
Goyarzu P, Malin DH, Lau FC, Tablialatela G, Moon WD, Jenings R, Moy E, Moy D, Lippold S, Shukitt-Hale B, Joseph JA
"Blueberry supplemented diet: effects on object recognition memory and nuclear factor-kappa B levels in aged rats", Nutritional Neuroscience, 2004, 7:75-83.

 Researchers from the Universidad Nacional Autonoma de Mexico, University of Houston-Clear Lake, University of Texas and Tufts University have found that a blueberry-enriched diet prevented an age-related increase in the protein NF-B, NF-B is a protein transcription factor that is elevated by aging and oxidative stress. The rats were maintained for four months on a control diet or a blueberry-enriched diet. In 4 out of 5 regions of the brain. The level NF-B in the aged rats on the blueberry-enriched diet and the young rats on the control differed significantly in only one region of the brain.
 
Blueberries and Aging 3
Written by Administrator    Thursday, 20 November 2008 14:53    PDF Print E-mail
Thursday, 20 November 2008 14:53
Spangler EL, Duffy K, Devan B, Guo Z, Bowker J, Shukitt-Hale B, Joseph JA, Ingram DK, Rats fed a blueberry-enriched diet exhibit greater protection against a kainate-induced learning impairment. Program No. 735.10. Abstract. Washington DC: Society for Neuroscience, 2003.

Rats were fed either a control diet or a diet supplemented with a 2% blueberry extract for 8-10 weeks. Rats were then injured in the dorsal hippocampus region of the brain. They were then evaluated in a maze task that was proven to be sensitive to aging and hippocampal dysfunction. All rats exhibited a learning impairment in the maze task after injury however the rats on the blueberry diet had significantly less impairment than that observed in the control diet group.
 
Blueberries and Aging 4
Written by Administrator    Thursday, 20 November 2008 15:10    PDF Print E-mail
Thursday, 20 November 2008 15:10
Youdim KA, Shukitt-Hale B, Martin A, Wang H, Denisova N, Bickford PC, Joseph JA. "Short-term dietary supplementation of blueberry polyphenolics: Beneficial effects on aging brain performance and peripheral tissue fuction," Nutritional Neuroscience, 2000, 3:383-397.

This study examined if blueberry extracts were able to ameliorate age-related declines in neuronal and cognitive function in laboratory animals fed a well balanced diet. After consuming diets supplemented with blueberry extract for eight weeks the subjects showed improvement in normal age related declines in behavioral parameters such as balance, coordination, working memory and reference memory.
 
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